Impacto de exposición de moléculas orgánicas derivadas de hidrocarburos en jóvenes universitarios

Autores/as

  • Ricardo Alberto Suárez Pérez Universidad Juárez Autónoma de Tabasco
  • José Arnold González-Garrido Universidad Juárez Autónoma de Tabasco
  • Adelma Escobar-Ramírez Universidad Juárez Autónoma de Tabasco
  • Eduardo De la Cruz-Cano Universidad Juárez Autónoma de Tabasco
  • Carlos Javier López-Victorio Universidad Juárez Autónoma de Tabasco

DOI:

https://doi.org/10.19136/jobs.a5n15.3565

Palabras clave:

hidrocarburos aromáticos policíclicos, obesidad, contaminantes ambientales

Resumen

Introducción. La exposición a moléculas orgánicas derivadas de hidrocarburos aromáticos policíclicos, se ha vinculado con la patogenesis de diferentes trastornos metabólicos como la obesidad y la diabetes mellitus tipo 2. Una hipótesis emergente se basa en que la exposición a disruptores endocrinosambientales juega un papel importante en la fisiopatología de estos trastornos al alterar la programación metabólica en estos individuos. Objetivo. Investigar la asociación entre los hidrocarburos aromáticos policíclicos con la obesidad en estudiantes universitarios. Resultados. Se identificó una banda en el espectro de 265 nm, correspondiente a las muestras de pacientes obesos, lo cual fue relacionado con la exposición a HAP. Tambien, se identificaron tres estudiantes con datos de proteinuria durante el examen general de orina. Conclusión. Los resultados obtenidos en esta investigación sugieren que la exposición a productos químicos altera el sistema endocrino contribuyendo al riesgo de obesidad.

Biografía del autor/a

Ricardo Alberto Suárez Pérez, Universidad Juárez Autónoma de Tabasco

División Académica de Ciencias Básicas, Laboratorio de Bioquímica y Biología Molecular, CICTAT, Universidad Juárez Autónoma de Tabasco, Cunduacán, Tabasco

José Arnold González-Garrido, Universidad Juárez Autónoma de Tabasco

Grupo de investigación Bioquímica y Biología Molecular

Adelma Escobar-Ramírez, Universidad Juárez Autónoma de Tabasco

Grupo de investigación Bioquímica y Biología Molecular

Eduardo De la Cruz-Cano, Universidad Juárez Autónoma de Tabasco

Secretaría de Salud, Hospital General de Comalcalco, Departamento de Laboratorio de Análisis Clínicos, Comalcalco, Tabasco

Carlos Javier López-Victorio, Universidad Juárez Autónoma de Tabasco

División Académica de Ciencias Básicas, Laboratorio de Bioquímica y Biología Molecular, CICTAT, Universidad Juárez Autónoma de Tabasco, Cunduacán, Tabasco

Citas

James PT: Obesity: the worldwide epidemic. Clinics in dermatology 2004, 22(4):276-280.

Yanovski JA: Obesity: Trends in underweight and obesity - scale of the problem. Nature reviews Endocrinology 2018, 14(1):5-6.

Kurisu S, Nitta K, Sumimoto Y, Ikenaga H, Ishibashi K, Fukuda Y, Kihara Y: Frontal QRS-T angle and World Health Organization classification for body mass index. Int J Cardiol 2018, 272:185-188.

Goodarzi MO: Genetics of obesity: what genetic association studies have taught us about the biology of obesity and its complications. The lancet Diabetes & endocrinology 2018, 6(3):223-236.

Fairbrother U, Kidd E, Malagamuwa T, Walley A: Genetics of Severe Obesity. Current diabetes reports 2018, 18(10):85.

Yun HR, Kim H, Park JT, Chang TI, Yoo TH, Kang SW, Choi KH, Sung S, Kim SW, Lee J et al: Obesity, Metabolic Abnormality, and Progression of CKD. American journal of kidney diseases : the official journal of the National Kidney Foundation 2018, 72(3):400-410.

Courtemanche C, Tchernis R, Ukert B: The effect of smoking on obesity: Evidence from a randomized trial. Journal of health economics 2018, 57:31-44.

Kohorst MA, Warad DM, Nageswara Rao AA, Rodriguez V: Obesity, sedentary lifestyle, and video games: The new thrombophilia cocktail in adolescents. Pediatric blood & cancer 2018, 65(7):e27041.

Kleinert M, Clemmensen C, Hofmann SM, Moore MC, Renner S, Woods SC, Huypens P, Beckers J, de Angelis MH, Schurmann A et al: Animal models of obesity and diabetes mellitus. Nature reviews Endocrinology 2018, 14(3):140-162.

Bullón-Vela MV, Abete I, Martínez JA, Zulet MA: Obesity and Nonalcoholic Fatty Liver Disease: Role of Oxidative Stress. In: Obesity. edn.: Elsevier; 2018: 111-133.

Polyzos SA, Kountouras J, Mantzoros CS: Obesity and nonalcoholic fatty liver disease: from pathophysiology to therapeutics. Metabolism 2018.

Breininger SP, Malcomson FC, Afshar S, Turnbull DM, Greaves L, Mathers JC: Effects of obesity and weight loss on mitochondrial structure and function and implications for colorectal cancer risk. The Proceedings of the Nutrition Society 2019, 78(3):426-437.

Nattenmuller CJ, Kriegsmann M, Sookthai D, Fortner RT, Steffen A, Walter B, Johnson T, Kneisel J, Katzke V, Bergmann M et al: Obesity as risk factor for subtypes of breast cancer: results from a prospective cohort study. 2018, 18(1):616.

Lavie CJ, Carbone S, Agarwal MA: An obesity paradox with myocardial infarction in the elderly. Nutrition (Burbank, Los Angeles County, Calif) 2018, 46:122-123.

Sensors (Basel, Switzerland).

Lee HJ, Choi EK: Risk of ischemic stroke in metabolically healthy obesity: A nationwide population-based study. 2018, 13(3):e0195210.

Yin W, Hou J, Xu T, Cheng J, Li P, Wang L, Zhang Y, Wang X, Hu C, Huang C et al: Obesity mediated the association of exposure to polycyclic aromatic hydrocarbon with risk of cardiovascular events. The Science of the total environment 2018, 616-617:841-854.

Hendryx M, Luo J: Latent class analysis of the association between polycyclic aromatic hydrocarbon exposures and body mass index. Environment international 2018, 121(Pt 1):227-231.

Varjani SJ, Joshi RR, Kumar PS, Srivastava VK, Kumar V, Banerjee C, Kumar RP: Polycyclicaromatic hydrocarbons from petroleum oil industry activities: effect on human health and their biodegradation. In: Waste Bioremediation. edn.: Springer; 2018: 185-199.

Škrbić B, Marinković V, Spaić S, Milanko V, Branovački S: Profiles of polycyclic aromatic hydrocarbons in smoke from combustion and thermal decomposition of poplar wood pellets and sawdust. Microchemical Journal 2018, 139:9-17.

van Drooge BL, Prats RM, Reche C, Minguillón M, Querol X, Grimalt JO, Moreno T: Origin of polycyclic aromatic hydrocarbons and other organic pollutants in the air particles of subway stations in Barcelona. Science of the total environment 2018, 642:148-154.

Hao X, Zhang X, Cao X, Shen X, Shi J, Yao Z: Characterization and carcinogenic risk assessment of polycyclic aromatic and nitro-polycyclic aromatic hydrocarbons in exhaust emission from gasoline passenger cars using on-road measurements in Beijing, China. The Science of the total environment 2018, 645:347-355.

Oranuba E, Deng H, Peng J, Dawsey SM, Kamangar F: Polycyclic aromatic hydrocarbons as a potential source of carcinogenicity of mate. Journal of environmental science and health Part C, Environmental carcinogenesis & ecotoxicology reviews 2019, 37(1):26-41.

Lam MM, Engwall M, Denison MS, Larsson M: Methylated polycyclic aromatic hydrocarbons and/or their metabolites are important contributors to the overall estrogenic activity of polycyclic aromatic hydrocarbon-contaminated soils. 2018, 37(2):385-397.

Vondráček J, Pivnička J, Machala M: Polycyclic aromatic hydrocarbons and disruption of steroid signaling: History, recent advances and open questions. Current Opinion in Toxicology 2018.

Hayakawa K: Chemistry of polycyclic aromatic hydrocarbons (PAHs), Nitropolycyclic aromatic hydrocarbons (NPAHs) and other oxidative derivatives of PAHs. In: Polycyclic Aromatic Hydrocarbons. edn.: Springer; 2018: 3-10.

Choi H, Dostal M, Pastorkova A, Rossner P, Jr., Sram RJ, Ho SM: Greater susceptibility of girls to airborne Benzo[a]pyrene for obesity-associated childhood asthma. Environment international 2018, 121(Pt 1):308-316.

Urióstegui-Flores A, García-Bravo MdlL, Pérez-Pinto A, Orea-Lara A: Measurement of parameters associated with metabolic syndrome in nursing students from Taxco, México. Revista de Salud Pública 2018, 20(3):334-339.

Obesity: preventing and managing the global epidemic. Report of a WHO consultation. World Health Organization technical report series 2000, 894:i-xii, 1-253.

Lean ME, Han TS, Morrison CE: Waist circumference as a measure for indicating need for weight management. BMJ (Clinical research ed) 1995, 311(6998):158-161.

Perkampus H-H: UV-VIS Spectroscopy and its Applications: Spr

Descargas

Publicado

2020-02-29

Número

Sección

Artículo científico